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4.2 Empathogens or Entactogens ( serotonin releasers)

4.3 Dissociatives

Commentary: These three groups of dissociatives have slightly different effects but also share similarities separating them from other classes of hallucinogens. They are markedly different from psychedelics such as LSD, where alert and fully conscious users experience cognitive distortion while simultaneously interacting with the "real world". Hallucinations from these dissociatives are generally only experienced in dark rooms or with eyes closed, unless at very high doses above what is normally consumed recreationally. Nitrous oxide has very different effects however, and even at low doses includes auditory distortions. Unlike with many other psychedelic chemicals, salvia users are generally not ambulatory and the experience is frequently dissociative. Often a very brief trance is entered, where the user experiences an intense and very realistic dream state. On the other hand, the effect of salvia on emotion has been reported to be less marked than that of true psychedelics.

4.4 Deliriant s ( anticholinergics)

Commentary: Anticholinergics are sometimes called "true hallucinogens". These substances are the most likely to produce what is traditionally thought of as a hallucination, namely seeing and hearing fully realistic objects, persons, and sounds that are not truly there, as opposed to color changes or other distortions in vision. However, they have a great number of strong, unpleasant and possibly life-threatening physiological effects as well, and thus are used very rarely for their hallucinogenic properties.

4.5 Antihistaminic s

4.6 Cannabinoids (CB-1 cannabinoid receptor agonists)

4.7 Other

Commentary: Although muscimol does not usually cause normal hallucinations, it has a tendency to put the user to sleep, during which the user is able to have very vivid dreams with good dream recall.

4.8 Other (hallucinogenic activity questioned)

5 Hallucinogenic plants, fungi, and animals

Among the most well-known hallucinogenic plants and fungi are:

Among the most well-known hallucinogenic animals are:





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