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The American Red Cross was established on May 21, 1881 by Clara Barton. Jane Delano (1862-1919) was the founder of the American Red Cross Nursing Service .
The blood collection and distribution of American Red Cross is regulated under Code of Federal Regulations Title 21 as a drug and computer systems associated with the collecting, testing, and distribution of blood products is regulated as a medical device.
The American Red Cross supplies roughly 50% of the donated blood in the United States.