Hsp70 is a family of heat shock proteins including HSP70, Bip and DnaK with an average molecular weight of 70 kDa. In most species there are many proteins that belong to the Hsp70 family. All Hsp70 proteins bind ATP. Research suggest that they play an important role in the transport of proteins across membranes. Their exact function is still unknown. Diagram of the domain structure of Hsp70.The molecular chaperones Hsp70 and Hsp90 are of crucial importance for the maturation and folding of a diverse set of substrate proteins (Wegele et al. 2004).
1 See also
- michondrial-import stimulation factor
2 External link
3 References
- Wegele H, Muller L, Buchner J. (2004). Hsp70 and Hsp90 - a relay team for protein folding. Rev Physiol Biochem Pharmacol 151:1-44
Heat shock proteins
