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Rather than in hypoxia, a more general term denoting a shortage of oxygen, ischemia is an absolute or relative shortage of the blood supply to an organ. Relative shortage means the mismatch of blood supply (oxygen delivery) and blood request for adequate oxygenation of tissue.
This can be due to:
As the carrier of oxygen (oxygen is mainly bound to hemoglobin) insufficient blood supply leads to hypoxic tissue (anoxic in case of no oxygen supply at all) with the consequence of necrosis which determines the celldeath.
Ischemia is a feature of heart diseases, transient ischemic attackTransient ischemic attacks TIA are caused by temporary disturbance of blood supply to a restricted area of brain and cause recurrent and brief (less than 24 hours) neurologic dysfunctions. If there are neurological symptoms persisting for more than 24 hous, cerebrovascular accidentThe article is about stroke as medical term. For other uses of stroke, see stroke (disambiguation). A stroke or cerebrovascular accident CVA occurs when the blood supply to a part of the brain is suddenly interrupted by occlusion (an ischemic stroke) or bs, and peripheral artery occlusive diseaseIn medicine ( vascular surgery), Peripheral artery occlusive disease (PAOD) is a collator for all disease caused by the obstruction of large peripheral arteries, which can result from atherosclerosis, inflammatory processes leading to stenosis, an embolis.
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