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Johannes Peter Müller ( July 14, 1801 - April 28, 1858), German physiologist and comparative anatomist, was born at Coblenz.

In 1819 he entered Bonn University, where he became privatdocent in 1824, extraordinary professor of physiology in 1826, and ordinary professor in 1830. In 1883 he removed to the university of Berlin, where he filled the chair of anatomy and physiology with great distinction until his death. Müller made numerous researches in various departments of physiology, and in particular he extended knowledge as to the mechanism of voice, speech and hearing, and as to the chemical and physical properties of lymph, chyleChyle is a milky fluid ( bodily fluid) consisting of lymph and emulsified fats. It is formed in the small intestine during digestion of ingested fatty foods and taken up by lymph vessels (lacteals) unlike other components of digested food that are conveye and bloodBlood is a circulating tissue composed of fluid plasma and cells ( red blood cells, white blood cells, platelets). Medical terms related to blood often begin in hemo or hemato ( BE: haemo and haemato from the Greek word for "blood". Blood of different spe.

The appearance of his Handbuch der Physiologie des Menschen between 1833 and 1840 (translated into English by Dr William Baly, and published in London in 1842) marked the beginning of a new period in the study of physiology. In it, for the first time, the results of human and comparative anatomy, as well as of chemistryChemistry is the science of matter and its interactions with energy (see physics, biology). Because of the diversity of matter (which is mostly atomic), Chemists are often engaged in the pursuit of studying how atoms interact to form molecules, and how mo and other departments of physical science, were brought to bear on the investigation of physiological problems.

The most important portion of the work was that dealing with nervous action and the mechanism of the senses. Here he stated the principle, not before recognized, that the kind of sensation following stimulation of a sensory nerve does not depend on the mode of stimulation but upon the nature of the sense-organ. Thus light, pressure, or mechanical stimulation acting on the retina and optic nerve invariably produces luminous impressions. This he termed the law of the specific energy of sense substances. In the later part of his life he chiefly devoted himself to comparative anatomy. Fishes and marine invertebrata were his favorite subjects. Müller numbered such distinguished scientists and physiologists as Hermann von HelmholtzHermann Ludwig Ferdinand von Helmholtz ( August 31, 1821 September 8, 1894) was a German physician and physicist. Helmholtz was the son of a gymnasium headmaster, Ferdinand Helmholtz, who had studied classical philology and philosophy, and who was a close, Emil du Bois-ReymondEmil du Bois-Reymond ( November 7, 1818 November 26, 1896), German physiologist, was born in Berlin. The Prussian capital was the place both of his birth and of his life's work, and he will always be counted among Germany's great scientific men; yet he wa, Theodor SchwannTheodor Schwann ( December 7, 1810 January 11, 1882) was a German physiologist, histologist and cytologist. Schwann was born in Neuss, Germany and studied medicine in Berlin under Johannes Peter Muller. There, in 1836, he discovered and prepared the first, Jacob Henle and KFW Ludwig among his pupils.

In addition to his Handbuch der Physiologie, his publications include:

After the death of JF Meckel (1781-1833) he edited the Archiv fur Anatomie und Physiologie.

This article incorporates text from the public domain 1911 Encyclopædia Britannica. 1911 Britannica

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