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Cracknell played the aging Maggie Beare, an independent and determined woman gradually becoming senile, with a tendency to forget previous things she has organised, or sudden decisions to go off wandering. Macdonald played her long-suffering care-giver son Arthur.
The storylines addressed the problem of aging and caring for somebody with Alzheimer's disease with a gentle humour that made the show a popular favorite with audiences.
Much of the humour derived from the show's secondary characters - Robert (Szeps) and Liz (Morris). Robert was Arthur's brother, the ' black sheep' of the family who would do anything to avoid looking after his mother. Liz was his acid-tongued wife who is credited with many of the funniest moments of the series.
In 2004, the creators of the show selected their favorite episodes - acknowleding that some of the episodes had become dated and lost much of their humour - and aired "The Best of Mother and Son" which was a success, and proves the timeless quality of the show.