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A pandemic or global epidemic is a disease that affects people or animals over an extensive geographical area (from Greek pan all + demos people). Technically speaking it should cover the whole globe and affect everyone.

1 Common killers and pandemics

Note that just because a disease kills a lot of people it is not necessarily a pandemic. Many diseases, for example cancer, kill large numbers of people, but they are in fact a number of diseases lumped together for the sake of convenience.

2 Pandemics through history

There have been a number of significant pandemics in human history, all of them generally zoonoses that came about with domestication of animals - such as smallpox, diphtheria, influenza and tuberculosis. There have been a number of particularly significant epidemics that deserve mention above the 'mere' destruction of cities:

The epidemic disease of wartime was typhus, sometimes called "camp fever" because of its pattern of flaring up in times of strife. (It is also known as "gaol fever" and "ship fever", for its habits of spreading wildly in cramped quarters, such as jails and ships.) Emerging during the Crusades, it had its first impact in Europe in 1489 in Spain. During fighting between the Christian Spaniards and the Muslims in Granada, the Spanish lost 3,000 to war casualties and 20,000 to typhus. In 1528 the French lost 18,000 troops in Italy and lost supremacy in Italy to the Spanish. In 1542, 30,000 people died of typhus while fighting the Ottomans in the Balkans. The disease also played a major role in the destruction of Napoleon's grande armée in Russia in 1811. Typhus also killed numerous prisoners in the Nazi concentration camps during World War II, including Anne Frank.

Encounters between European explorers and populations in the rest of the world often introduced local epidemics of extraordinary virulence. Disease killed the entire native (Guanches) population of the Canary Islands in the 16th century. Half the native population of Hispaniola in 1518 was killed by smallpox. Smallpox also ravaged Mexico in the 1520s, killing 150,000 in Tenochtitlán alone, including the emperor, and Peru in the 1530s, aiding the European conquerors. Measles killed a further two million Mexican natives in the 1600s. As late as 1848-49, as many as 40,000 out of 150,000 Hawaiians are estimated to have died of measles, whooping cough and influenza.

There are also a number of unknown diseases that were extremely serious but have now vanished, so the etiology of these diseases cannot be established. Examples include the previously mentioned plague in 430 BCE Greece and the English Sweat in 16th-century England, which struck people down in an instant and was more greatly feared even than the bubonic plague.





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