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Home > Perverse effects of vaccination


Perverse effects of vaccination programmes manifest themselves when insufficient numbers of susceptibles are vaccinated to reach the critical threshold value (denoted qc) at which enough people are immune to the disease that its spread through the population (even to susceptible individuals) is stopped. This effect is commonly known as herd immunity.

If a vaccination programme does not attain qc, its effect is not to prevent the spread of the disease, but only to increase the average age at which individuals are infected. In diseases that have an increased severity or risk of complications with increased age, therefore, such a vaccination programme may actually increase the number of deaths from and problems relating to the disease. These are the perverse effects.


Some infectious diseases that increase in severity with age:


See also

Epidemiology



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