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The fluid is usually secreted by Cowper's glands during foreplay or at an early stage during sex, some time before the man reaches orgasm and semen is ejaculated. Pre-ejaculatory fluid prepares the urethra for the passage of semen and neutralizes the pH of any residual urine. It also lubricates the movement of the foreskin over the glans. The amount of fluid that the human male can issue varies widely between individuals, from imperceptible amounts to a copious flow.
A problem for couples who seek to avoid pregnancy, however, is that the pre-ejaculate may contain sperm. This is one additional reason why withdrawal ( coitus interruptus) is not considered to be a reliable method of birth control. However, some research has been done which suggests that there are no live sperm.
Andrology