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In biochemistry, to specify the primary structure of an unbranched biopolymer, such as a molecule of DNA, RNA or protein, is to name the species of every subunit ( nucleotide or amino acid) in order from the beginning to the end of the molecule to obtain either nucleotide or peptide sequence. The primary structure, in other words, is a biopolymer's exact chemical composition and to the sequence in which its subunits are arranged.

While the primary structure of a biological polymer to a large extent determines the three-dimensional shape that the molecule assumes in vivo, knowing it often doesn't help a person either to deduce this shape (known as the tertiary structure) or to predict localized structuring, such as the formation of loops or helices (called secondary structure). However, knowing the structure of a similar sequence (for example a member of the same Protein family) can competely identify the tertiary structure of the given sequence. Sequence families are often determined by Sequence clustering, and so structural genomics projects aim to produce a set of representative structurs to cover the sequence space ( non-redundant sequences ).

See also : sequencing -- DNA sequenceA DNA sequence (sometimes genetic sequence is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, The possible letters are A C G and T representing the four nucleotide subunits of a DNA strand ( ade -- protein sequencingProteins are found in every cell and are essential to every biological process, protein structure is very complex: determining a protein's structure involves first protein sequencing determining the amino acid sequences of its constituent peptides; and al -- secondary structure -- tertiary structure -- quaternary structureIn biochemistry, many proteins are actually assemblies of more than one protein molecule, which in the context of the larger assemblage are known as protein subunits. In addition to the tertiary structure of the subunits, multiple-subunit proteins possess -- translation

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Topics: Primary Structure Sequence Protein Molecule Tertiary Sequencing...

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