Unlike a speedball, a primo does not combine an upper (the cocaine) with a depressant (i.e. heroin), but instead with a much more benign substance ( THC). Smoking primo is likely to be less harmful than smoking straight cocaine due to lower dosages, and far less harmful than a speedball.
The term primo comes from the Spanish word for "cousin." A primo is known in some parts of the world as a "New Yorker".
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