Home > Pseudoephedrine
Pseudoephedrine is a sympathomimetic amine commonly used as a decongestant. The salts pseudoephedrine hydrochloride and pseudoephedrine sulfate are found in many over-the-counter preparations either as single-ingredient preparations, or more commonly in combination with antihistamineAn antihistamine is a chemical which serves to reduce or eliminate effects mediated by histamine, an endogenous chemical of the human body released during allergic reactions, at the histamine receptor. It can be administered locally (through the skin, noss and/or paracetamol/ ibuprofenIbuprofen is a nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhoea, pyrexia; and as an analgesic, especially where there is an inflammatory component. Ibuprofen was developed by the research arm of Boots.. This agent is often referred to by consumers as Sudafed, which is the trade name for a common brand of pseudoephedrine hydrochloride.
Unlike antihistamineAn antihistamine is a chemical which serves to reduce or eliminate effects mediated by histamine, an endogenous chemical of the human body released during allergic reactions, at the histamine receptor. It can be administered locally (through the skin, noss, which modify the systemic histamineHistamine is a monoamine chemical involved in local immune responses. Chemical properties Chemically, histamine is 2-(4-imidazolyl)ethylamine and has the formula C H N. Histamine is synthesized by the decarboxylation of the amino acid histidine, a reactio-mediated allergicThis article deals specifically with IgE mediated hypersensitivity. For other types of allergic or hypersensitive reactions see the main article: Hypersensitivity An allergy or Type I hypersensitivity is a immune malfunction whereby a person's body is hyp response, pseudoephedrine only serves to relieve nasal congestion commonly associated with coldThe common cold is a mild viral infectious disease of the nose and throat, the upper respiratory system. Its symptoms are sneezing, sniffing, running/blocked nose (often these occur simultaneously, or one in each nostril), scratchy, sore, or phlegmy throas or allergiesThis article deals specifically with IgE mediated hypersensitivity. For other types of allergic or hypersensitive reactions see the main article: Hypersensitivity An allergy or Type I hypersensitivity is a immune malfunction whereby a person's body is hyp. The advantage of oral pseudoephedrine over topical nasal preparations, such as oxymetazoline , is that it does not cause rebound congestion ( rhinitis medicamentosa ).
1 Nomenclature
Pseudoephedrine is the International Nonproprietary Name (INN) of the (1S,2S)- diastereomer of ephedrine (which has 1R,2S- configuration). Equivalent names are (+)-pseudoephedrine and D-pseudoephedrine.
(-)-Pseudoephedrine or L-pseudoephedrine then designates the enantiomer of pseudoephedrine.
